一项对95,559名参与者的大规模研究发现，快速眼动（REM）睡眠时间延长与包括痴呆症、心力衰竭和帕金森病在内的83种疾病风险降低相关1。研究人员利用腕部加速度计对参与者进行连续7天7夜的监测1，随访中位数为8.9年，期间检测了1000多种疾病结果1。REM睡眠增加47.6分钟与心力衰竭风险比0.74、痴呆症风险比0.54、帕金森病风险比0.20的降低相关联1。
深度睡眠也显示出保护作用，与2型糖尿病和重度抑郁症等7种疾病风险降低相关1。研究表明，总睡眠时长与多种疾病风险存在非线性关系，每晚6至8小时的睡眠时长风险最低1。相比之下，每晚睡眠少于5小时与37种疾病风险增加相关1。这项研究于2026年9月17日发表于《PLOS Medicine》期刊1，研究人员结论认为，维持6至8小时睡眠时长可有效降低多种疾病风险1。
A large-scale study involving 95,559 participants from the UK Biobank wearing wrist accelerometers for seven consecutive days and nights found that increased REM sleep duration is associated with reduced risk across 83 diseases, including dementia, heart failure, and Parkinson's disease.1 An additional 47.6 minutes of REM sleep per night correlated with notably lower risks for heart failure (hazard ratio 0.74), dementia (hazard ratio 0.54), and Parkinson's disease (hazard ratio 0.20).1 Deep sleep showed independent protective effects, being linked to reduced risk for seven conditions including type 2 diabetes and major depression.1
The research, published in PLOS Medicine on September 17, 2026, examined over 1,000 disease outcomes across the follow-up period with a median duration of 8.9 years.1 The findings revealed a non-linear relationship between total sleep duration and disease risk, with the 6 to 8-hour nightly sleep window showing the lowest risk profile.1 In contrast, sleeping fewer than five hours per night was associated with increased risk for 37 diseases.1 The study's authors concluded that "maintaining 6 to 8 hours of sleep duration can effectively reduce the risk of multiple diseases."1
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