埃默里大学的一项研究发现，患有睡眠障碍和轻度认知障碍的老年人每日服用至少5000国际单位维生素D，其在蒙特利尔认知评估测试中的得分比未服用者高13%以上1。这项研究纳入54名患有睡眠障碍和轻度认知障碍的成年人1，结果表明维生素D补充剂可能值得进一步研究，作为认知衰退早期阶段的潜在可调节因素1。
研究还显示，维生素D2和D3在改善认知功能方面表现相似1。由美国国立卫生研究院下属国家衰老研究所资助的这项研究，已发表在《睡眠医学》杂志2026年第146卷中1。美国目前有超过700万人患有阿尔茨海默病痴呆症，预计到2050年将增至近1300万人1，其中阿尔茨海默病中度至重度患者中50%报告睡眠障碍1，这一发现为认知衰退的干预提供了新的研究方向。
Researchers at Emory University have found a significant association between vitamin D supplementation and improved cognitive performance in older adults with sleep disorders and mild cognitive impairment. Participants who took at least 5,000 international units of vitamin D daily scored more than 13% higher on the Montreal Cognitive Assessment compared to those who did not supplement 1. The study enrolled 54 adults with both sleep disturbances and mild cognitive impairment, and found that both vitamin D2 and D3 variants produced similar cognitive improvements 1.
The findings suggest that vitamin D supplementation may warrant further investigation as a potentially modifiable factor in the early stages of cognitive decline 1. This research comes at a time when cognitive impairment poses a growing public health challenge—currently, more than 7 million Americans have Alzheimer's disease dementia, a figure expected to rise to nearly 13 million by 2050 1. Sleep disorders compound this concern, as 50% of patients with moderate to severe Alzheimer's disease report experiencing sleep disturbances 1. The study was funded by the National Institute on Aging, part of the National Institutes of Health, and was published in Sleep Medicine in 2026, Volume 146, Article 108960 1.
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