一项发表于《JAMA Psychiatry》的新报告指出，全球神经性厌食症和贪食症的发病率在1990年至2023年间增加了71% 1。截至2023年，估计有1810万人患有这两种进食障碍之一，这些疾病在当年造成了相当于约383万个健康生命年的损失（DALYs） 1。研究人员预测，到2050年，受影响人数可能达到2180万 1。该报告的主要作者包括来自南京医科大学儿童医院（Children’s Hospital of Nanjing Medical University）的Ruhai Bai 1。
临床心理学家警告称，GLP-1类减肥药的广泛使用可能加剧这一问题 1。一项小型研究显示，30%有进食障碍的人曾使用过GLP-1药物，其中10%疑似滥用 1。此外，社交媒体算法推送的“有毒”内容以及新冠疫情期间的隔离也是导致发病率上升的重要因素 1。墨尔本大学的研究发现，TikTok上有进食障碍的用户比无此问题的用户多收到4343%的“有毒”进食障碍视频 1。
专家建议医生在开具GLP-1药物前筛查进食障碍风险 1。Cynthia Bulik提出了这一建议 1。Cheri Levinson观察到，出现进食障碍的最年轻患者低至8岁或9岁，甚至有11岁儿童通过TikTok购买此类药物 1。
A new report published in JAMA Psychiatry reveals that the global incidence of anorexia nervosa and bulimia rose by 71% between 1990 and 2023 1. By 2023, an estimated 18.1 million people were affected by these eating disorders, which resulted in approximately 3.83 million disability-adjusted life years (DALYs) lost 1. Researchers project that the number of individuals suffering from these conditions could reach 21.8 million by 2050 1. The study identifies several contributing factors to this increase, including isolation during the COVID-19 pandemic and "toxic" content amplified by social media algorithms 1.
Clinical psychologists warn that the widespread use of GLP-1 weight-loss medications may exacerbate the crisis. A small study indicated that 30% of individuals with eating disorders had used GLP-1 drugs, with 10% showing signs of potential misuse 1. Cynthia Bulik has advised physicians to screen patients for eating disorder risks before prescribing GLP-1 medications 1. The impact of digital platforms is also significant; research from the University of Melbourne found that TikTok users with eating disorders received 4,343% more "toxic" eating disorder videos compared to those without such issues 1.
The trend is affecting increasingly younger demographics. Cheri Levinson reported observing the youngest eating disorder patients at ages eight or nine, noting cases where even 11-year-olds have purchased these medications via TikTok 1. Ruhai Bai from the Children’s Hospital of Nanjing Medical University was among the authors associated with the publication of the report and the raising of these warnings 1.
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