美国神经病学学会发表的一项七年追踪研究表明,帕金森病患者的运动量与认知和运动症状的恶化速度存在关联。1该研究对294名患有轻度至中度帕金森病的成年人进行了长期监测,参与者平均年龄为66岁。1
研究结果显示,每周锻炼超过8小时的患者认知功能年均变化仅为0.007分(满分30分),而每周锻炼不超过4小时的患者年均认知下降0.478分。1在帕金森病运动症状评分上,最活跃的患者组年降0.783分,而最不活跃的患者组则年增0.143分。1
研究主要作者Dong-Woo Ryu博士指出:"我们的研究发现体育活动可能具有双重益处,与运动和认知能力衰退放缓有关。"1研究人员同时指出,体育活动水平基于参与者的自我报告而非直接测量,因此尚未证实运动直接导致帕金森病病程减缓。1该研究于2026年10月7日发表在《神经病学》杂志上。1
A seven-year study published in Neurology has found that physical activity levels among Parkinson's disease patients correlate inversely with the rate of cognitive and motor symptom decline.1 Researchers at the University of Cincinnati tracked 294 adults with mild to moderate Parkinson's disease, with an average age of 66 years, to examine the relationship between exercise frequency and disease progression.1
The findings revealed substantial differences across activity levels.1 Patients exercising more than eight hours per week showed minimal cognitive decline, with scores declining by only 0.007 points annually on a 30-point scale, compared to 0.478 points yearly for the least active group exercising four hours or fewer per week.1 The moderately active group, exercising between four and eight hours weekly, experienced intermediate cognitive decline of 0.090 points per year.1 Motor symptom scores on a 0-132 scale demonstrated similar patterns: the most active group improved by 0.783 points annually, the moderately active group improved by 0.225 points, while the least active group deteriorated by 0.143 points yearly.1
According to Dr. Dong-Woo Ryu, the study's lead author, "Our research found that physical activity may offer dual benefits, associated with slowed motor and cognitive decline."1 However, researchers cautioned that the study does not definitively prove that exercise directly slows disease progression, as activity levels were based on participants' self-reported measures rather than direct measurement.1 The study was published on October 7, 2026.1
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