仅七天力量训练即可在小鼠体内启动脂肪分解

巴西坎皮纳斯州立大学的研究发现，短短七天的力量训练就能在小鼠体重保持不变的情况下，激活脂肪分解的分子通路，从而缩小内脏脂肪细胞的体积1。这项研究表明，力量训练带来的代谢益处会先于体重下降而出现。

该研究对雄性小鼠进行了为期七天、共七次的训练课程，训练方式为小鼠尾部负重爬升70厘米楼梯，强度达到最大功率的70%，每组包含20次爬升，组间间隔60至90秒1。实验涵盖了标准饮食组和高脂肪饮食诱导肥胖组两类小鼠。研究发现，力量训练激活了PLIN1、ABHD5和ATGL等脂肪分解蛋白，同时降低了促进脂肪积累的Scd1基因表达水平，减少了肠道周围的内脏脂肪沉积1。

研究者Leandro Moura表示："即使七天力量训练后还没有体重下降，促进脂肪积累的分子通路活性降低，刺激脂肪分解的通路活性升高"1。不过研究人员强调，这些在小鼠身上观察到的成果仍需在人类研究中得到验证1。该研究已发表在《生命科学》杂志2026年第401卷，并由圣保罗州研究基金会资助1。

Researchers at Campinas State University in Brazil have demonstrated that a mere seven days of strength training can activate fat-burning molecular pathways and reduce the size of visceral fat cells in obese mice, even without weight loss 1. The study, which consisted of seven training sessions over one week, reveals that metabolic benefits of strength training begin before visible weight reduction occurs 1.

In the experiment, male mice—both those on a standard diet and those with diet-induced obesity—performed a strength training protocol involving climbing a 70-centimeter staircase while carrying weight on their tails at 70 percent maximum power, completing 20 ascents with 60 to 90-second intervals between repetitions 1. The training activated key fat-breakdown proteins including PLIN1, ABHD5, and ATGL, while simultaneously reducing expression of the Scd1 gene, which decreases visceral fat deposits surrounding the intestines 1. According to researcher Leandro Moura, "Even after just seven days of strength training without weight loss, the molecular pathways promoting fat accumulation showed reduced activity, while the pathways stimulating fat breakdown showed increased activity" 1.

The findings, published in Life Sciences in 2026, were supported by the São Paulo Research Foundation (FAPESP) 1. The researchers note that these results require validation in human studies before broader conclusions can be drawn 1.