德克萨斯农工大学的Dog Aging Project研究发现，狗血液中的代谢分子模式与寿命长短的关联方式与人类存在惊人相似性1。研究人员分析了数千种代谢物，发现某些组合与狗的早期或晚期死亡相关联，这些模式与已发表的5项大规模人类死亡率研究结果基本一致1，表明狗和人类在衰老生物学上共享重要特征1。
该研究主要关注代谢、炎症和细胞应激等生物过程1。德克萨斯农工大学的Kate Creevy博士指出，"狗身上有风险的分子或对抗早期死亡的保护性分子与人类中的分子非常相似"1。相关研究已发表于《The Journals of Gerontology》2026年第81卷第4期1。
Dog Aging Project是一项全国性长期研究，追踪美国各地宠物狗的生活1。
Researchers at Texas A&M University's Dog Aging Project have discovered striking parallels between canine and human aging, finding that patterns of metabolic molecules in dogs' blood relate to lifespan in remarkably similar ways to those observed in people 1. The team analyzed thousands of metabolic compounds and identified specific combinations associated with earlier or later death in dogs—patterns that align substantially with findings from five major human mortality studies 1. According to Dr. Kate Creevy, risk molecules detected in dogs or protective molecules guarding against early death bear close resemblance to their human counterparts 1, suggesting that dogs and humans share fundamental biological features in aging.
The research, published in The Journals of Gerontology Volume 81, Issue 4 in 2026, focused on metabolic processes, inflammation, and cellular stress as key drivers of aging 1. While dogs typically live 12 to 13 years compared to human lifespans exceeding 70 years, the underlying molecular signatures of aging appear conserved across species 1. The Dog Aging Project itself represents a nationwide long-term effort tracking the lives of pet dogs across the United States 1, providing a valuable model for understanding longevity mechanisms that could ultimately benefit human health.
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