加州大学圣迭戈分校的研究表明，开始使用大麻的青少年在记忆、注意力、语言和处理速度方面的发展速度明显慢于未使用者。[1]这项基于11036名参与者的纵向研究追踪了儿童从9-10岁到16-17岁期间的认知能力变化，发现使用大麻的青少年认知能力增长趋缓，而对照组则继续改善。[1]研究特别指出，含有THC的大麻使用与更大程度的记忆性能下降相关联。[1]
该研究已调整分析以考虑家庭背景、心理健康、其他物质使用和基线认知能力等混淆因素。[1]值得注意的是，在CBD暴露组中未观察到相同的认知发展缓慢模式，但该组参与者数量有限。[1]这项研究由加州大学圣迭戈分校精神医学系助理教授Natasha Wade博士领导，已发表于《神经精神药理学》期刊2026年第51卷第9期。[1]
Researchers at the University of California, San Diego have found that adolescents who begin using cannabis show slower development in memory, attention, language, and processing speed compared to non-users.[1] The study, based on longitudinal data from the ABCD research project tracking over 11,000 participants from ages 9–10 to 16–17, revealed that while cognitive abilities continued to improve in a control group, those using cannabis experienced a deceleration in cognitive gains.[1] THC was identified as the primary factor driving memory deterioration among cannabis users.[1]
The research team, led by Dr. Natasha Wade, an assistant professor in the Department of Psychiatry at UC San Diego, controlled for confounding variables including family background, mental health status, other substance use, and baseline cognitive ability to isolate the effects of cannabis exposure.[1] Notably, the study did not observe the same pattern among those exposed to CBD alone, though this group had limited participants.[1] The findings were published in Neuropsychopharmacology, Volume 51, Issue 9, in 2026.[1]