澳大利亚研究团队正在开发口服诱饵疫苗，以保护塔斯马尼亚恶魔及其他食腐哺乳动物免受面部肿瘤疾病及禽流感威胁 1。该团队自2019年开始开发针对塔斯马尼亚恶魔面部肿瘤疾病的口服诱饵疫苗 1。官方估计，高达10%的澳大利亚哺乳动物物种面临禽流感高风险至极高风险 1。
在澳大利亚，褐贼鸥是首个被发现感染禽流感的物种 1。去年，H5N1禽流感抵达澳大利亚赫德岛后，超过1.3万只南象海豹幼崽死亡 1。目前，澳大利亚仅有一种禽流感疫苗获批用于小蓝企鹅和圈养鸟类的紧急使用 1。此外，美国研究人员已试验一种将禽流感靶点插入弱化人类病毒的新疫苗，在小鼠和牛身上显示出保护效果 1。自1978年以来，欧洲30个国家已分发10亿份口服狂犬病疫苗诱饵，研究人员呼吁借鉴这一成功经验，加快野生动物禽流感疫苗的研发与审批 1。
Official estimates indicate that up to 10% of Australian mammal species are at high to very high risk of avian influenza 1. The brown skua was the first species in Australia found to be infected with the virus 1. Last year, after H5N1 avian influenza reached Heard Island, over 13,000 southern elephant seal pups died 1. Currently, Australia has only one avian influenza vaccine approved for emergency use in little penguins and captive birds 1.
To address these threats, an Australian research team is developing oral bait vaccines for Tasmanian devils and other scavenging mammals to protect them from facial tumor disease and avian influenza 1. The team has been working on the oral bait vaccine for facial tumor disease in Tasmanian devils since 2019 1. In related efforts, U.S. researchers have tested a new vaccine that inserts avian influenza targets into a weakened human virus, demonstrating protective effects in mice and cattle 1. Drawing on the success in Europe, where 30 countries have distributed one billion oral rabies vaccine baits since 1978, researchers are urging the acceleration of the development and approval processes for wildlife avian influenza vaccines 1.
评论
还没有评论，欢迎留下第一条。