卢德大学的长期脑部研究表明，吸烟、高血压、心脏病和高血脂等常见的可改变风险因素与脑血管损伤密切相关[1]。该研究跟踪了近500名平均年龄65岁的参与者四年时间，发现大多数可改变的风险因素与脑血管损伤和白质变化的加速积累相关联[1]。
研究还发现糖尿病与淀粉样β蛋白积累增加相关[1]。这些发现表明，采取健康的生活方式选择可能有助于延缓痴呆症的发生[1]。该研究已发表在《阿尔茨海默病预防杂志》2026年第13卷第2期上[1]。
A long-term brain study conducted at Lund University has identified a significant connection between common cardiovascular and lifestyle risk factors and brain damage associated with dementia.[1] Researchers followed nearly 500 participants with an average age of 65 years over a four-year period and found that most modifiable risk factors—including smoking, high blood pressure, heart disease, and high cholesterol—were associated with accelerated accumulation of cerebrovascular damage and white matter changes in the brain.[1]
The findings suggest that adopting healthier lifestyle choices could potentially slow the onset of dementia.[1] Additionally, the study revealed that diabetes was linked to increased accumulation of amyloid-beta protein, another hallmark of Alzheimer's disease pathology.[1] The research was published in The Journal of Prevention of Alzheimer's Disease, volume 13, issue 2, article number 100448, in 2026.[1]