波士顿儿童医院及合作机构的研究发现，COVID-19感染可以重新激活人体内潜伏的多种病毒。1这项由15家美国生物医学研究机构参与的研究跟踪了1,154名患者，收集了超过200,000份样本，产生超过10亿个数据点。1研究人员在患者入院后40天内识别了11种被重激活的病毒，其中包括Epstein-Barr病毒、单纯疱疹病毒1型、巨细胞病毒和Anelloviridae病毒等。1
研究结果显示，Anelloviridae病毒的重激活与长期身体残疾和长期COVID的发生存在明显关联。1研究发现Epstein-Barr和巨细胞病毒似乎因炎症反应而被重激活，而非因免疫抑制。1研究主导者Ofer Levy指出，估计超过1,000万美国成年人患有长期COVID。1
Researchers from Boston Children's Hospital and 14 other U.S. biomedical institutions have discovered that COVID-19 can reactivate latent viruses dormant in the human body.1 The study tracked 1,154 patients and collected more than 200,000 samples, generating more than 1 billion data points to identify viral reactivation patterns.1 Within 40 days of hospitalization, investigators identified 11 reactivated viruses, with the most frequently detected being Epstein-Barr virus, herpes simplex virus type 1, cytomegalovirus, and Anelloviridae virus.1
The findings suggest that reactivation of Anelloviridae virus showed a significant association with long-term physical disability and long COVID development.1 In contrast, research indicated that Epstein-Barr and cytomegalovirus appeared to reactivate due to inflammatory responses rather than immune suppression.1 According to study leader Ofer Levy, an estimated 50,000 Americans may die from COVID during the 2025-2026 respiratory season, with over 10 million American adults believed to have long COVID.1
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