爱荷华大学的研究团队发现,大脑的额顶叶皮层在面对不确定性时,会动态调整与其他脑区的通讯方式,而非单纯增加活动强度1。研究人员利用计算模型和脑成像技术,对38名年龄在18至35岁的参与者进行了实验1。该研究发现,这一信息枢纽能够根据决策过程各阶段所需的信息类型,灵活重组其神经连接1。
研究团队负责人卡·黄表示:"我们观察到这个网络在困难任务中并不是简单地变得更活跃,而是根据决策的每个阶段需要什么信息而动态改变与其他脑区的通讯方式"1。该研究发表于2026年《神经科学杂志》第46卷第30期1,获得了国家心理健康研究所和爱荷华神经科学研究所的资助1。研究人员指出,这些发现可能为理解注意力缺陷多动障碍和精神分裂症等神经精神疾病提供新的科学依据1。
Scientists at the University of Iowa have discovered that the brain's frontoparietal cortex does not simply increase its activity when faced with uncertainty, but instead flexibly reorganizes how it communicates with other brain regions depending on the specific information needed during decision-making.1 The research team, led by Kai Hwang, used computational modeling and brain imaging to examine 38 participants aged 18–35, finding that this neural hub dynamically adjusts its network connections based on each stage of the decision process.1 According to Hwang, "Rather than simply becoming more active during difficult tasks, we observed how this network dynamically changes how it communicates with other brain regions depending on what information is needed at each stage of a decision."1
The study, published in the Journal of Neuroscience in 2026, was conducted by first author Stephanie C. Leach and supported by funding from the National Institute of Mental Health and the Iowa Neuroscience Institute.1 These findings offer potential insights into neurological and psychiatric conditions such as ADHD and schizophrenia, suggesting that dysfunction in this adaptive communication mechanism may contribute to symptoms observed in these disorders.1
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