38岁的王女士怀孕双胞胎，在孕22+1周时第一个胎儿的羊膜囊发生破裂并伴有感染[1]。中山大学附属第七医院妇产科采取延迟分娩策略，在孕22+3周时将感染的第一个胎儿娩出，同时保留第二个胎儿继续在宫内妊娠[1]。
这一方案得以实施的前提是该患者属于双绒双羊胚胎，意味着两个胎儿各自拥有独立的胎盘和羊膜囊，彼此互不相通[1]。经过医疗团队105天的精密监护和治疗，第二个胎儿最终在孕37+3周时健康出生[1]。据悉，双胎延迟分娩的成功率仅为14/10万[1]。
A 38-year-old woman carrying twins received a rare medical intervention at Zhongshan University Affiliated Seventh Hospital after her first fetus developed complications early in pregnancy.[1] When the pregnancy reached 22 weeks and 1 day of gestation, the first fetus's amniotic sac ruptured and became infected.[1] Rather than delivering both twins immediately, the obstetric team opted for a delayed delivery strategy, delivering the infected first fetus at 22 weeks and 3 days of gestation while preserving the second fetus to continue developing in the womb.[1]
The successful continuation of the second pregnancy was made possible by the unique characteristics of the twin pregnancy: both fetuses were diamniotic dichorionic, meaning each had its own independent placenta and amniotic sac that did not communicate with each other.[1] Over the following 105 days, the medical team provided intensive monitoring and treatment to protect the developing second fetus.[1] The second twin was ultimately delivered via cesarean section at 37 weeks and 3 days of gestation in good health, following rupture of the second amniotic membrane.[1] This delayed delivery procedure, with a reported success rate of 14 per 100,000 twin pregnancies, represents a significant achievement in maternal-fetal medicine.[1]
