美国疾病控制与预防中心发布了首项全国性研究,揭示侵入性霉菌感染的患病情况可能远未被充分认识1。研究团队在2020年至2024年间对亚特兰大地区医院进行了调查,最初识别出近1000例疑似病例,经过确认后约有450例确诊患者,其中大约三分之一的患者死亡1。CDC高级作者Jeremy Gold医生表示:"这是我们第一次有这样的估计"1。
根据研究数据,医院预期的侵入性霉菌感染发病率约为每100张住院床位每年3至5例1。老年人、癌症患者、免疫系统受损者以及COVID-19患者被列为高危人群1。CDC之前的估计显示,每年有超过15000例住院与侵入性霉菌病相关1。随着气候变化导致洪水和飓风频率上升,加之全球人口老龄化加剧,专家认为这一问题在未来可能会进一步恶化1。Duke大学研究员Jeffrey Jenks医生也认同这一趋势,指出"真菌感染的频率可能会随气候变化增加"1。
The U.S. Centers for Disease Control and Prevention has released its first nationwide study examining the prevalence of invasive fungal infections, suggesting the threat posed by mold-related illnesses may be substantially underestimated.1 Researchers examined hospitals in the Atlanta area over a five-year period from 2020 to 2024, initially identifying nearly 1,000 cases and ultimately confirming approximately 450 cases of invasive mold infection.1 Among confirmed patients, roughly one-third died from the condition.1
Hospital data collected during the study period indicates an expected disease rate of 3 to 5 cases per 100 hospital beds annually.1 The CDC's prior estimates suggest more than 15,000 hospitalizations annually are associated with invasive fungal disease.1 According to Dr. Jeremy Gold, a senior author on the research, "This is the first time we have had an estimate like this."1 Elderly patients, individuals with cancer, those with compromised immune systems, and COVID-19 patients are identified as particularly vulnerable populations.1
Researchers point to climate change as a potential driver of increased risk, with more frequent flooding and hurricanes expected to amplify exposure to mold.1 Combined with an aging population, these factors suggest the burden of invasive fungal infections may worsen in the coming years.1 Dr. Jeffrey Jenks, a researcher at Duke University, stated: "I agree that the frequency of fungal infections will likely increase with climate change."1
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