世界卫生组织呼吁疟疾流行国加强抗疟药物疗效监测

世界卫生组织发布了《全球抗疟药物疗效和耐药性报告（2000-2010）》，呼吁疟疾流行国加强对抗疟药物疗效的监测工作。1该报告基于过去十年1100项研究，由各国疟疾控制项目和研究机构共同开展。1

报告数据显示，仅有34%的疟疾流行国遵循世界卫生组织的建议进行常规监测。1世界卫生组织已在2009年2月确认，柬埔寨-泰国边境出现了青蒿素耐药性，同时缅甸-泰国边境也有早期证据表明可能出现青蒿素耐药性。1尽管存在这些风险，青蒿素类联合疗法（ACT）目前的治愈率仍大于90%。1世界卫生组织计划在2011年1月发布《全球青蒿素耐药性遏制计划》，以应对这一威胁。1自1973年以来，世界卫生组织一直为各国疟疾控制项目提供药物耐药性监测支持。1

The World Health Organization released its Global Report on Antimalarial Drug Efficacy and Drug Resistance (2000–2010), calling on malaria-endemic countries to intensify surveillance of antimalarial drug effectiveness to detect artemisinin resistance early 1. The report, based on over 1,100 studies conducted by national malaria control programs and research institutions over the past decade, revealed that only 34 percent of malaria-endemic countries followed WHO recommendations for routine monitoring 1.

The findings documented emerging resistance concerns. In February 2009, the WHO confirmed the presence of artemisinin resistance at the Cambodia-Thailand border, with early evidence also suggesting possible artemisinin resistance at the Myanmar-Thailand border 1. Despite these developments, artemisinin-based combination therapies (ACTs) currently maintain a cure rate exceeding 90 percent 1. The WHO cautioned that artemisinin resistance poses a risk of spreading to Africa 1. The organization plans to release the Global Plan to Combat Artemisinin Resistance in January 2011 1. Since 1973, the WHO has provided support to national malaria control programs for drug resistance monitoring 1.