贝勒医学院研究人员在《自然》杂志发表的最新研究发现，即使患者处于全身麻醉的无意识状态，其大脑仍能进行复杂的语言分析1。研究团队使用Neuropixels探针监测了接受癫痫手术患者麻醉期间海马体数百个神经元的电信号，发现大脑不仅能够识别词性差异、区分名词和动词等词汇类别，还能根据上文预测句子中的下一个词1。此外，海马体神经元对意外声音的反应模式也各不相同1。
研究者Sameer Sheth教授表示，"大脑在无意识状态下比之前认为的要活跃和有能力得多"1。这一发现挑战了人们对意识与思维关系的传统理解。研究团队指出，这项工作可能为语音假肢技术奠定基础，从而帮助神经损伤患者恢复沟通能力1。不过研究人员也强调，实验仅在一种特定麻醉方式下进行，相关结果不能自动推广到其他麻醉方法或其他无意识状态1。
Researchers at Baylor College of Medicine have discovered that the human brain continues to perform complex linguistic analysis even while under general anesthesia, challenging conventional understanding of consciousness and cognition.1 Using Neuropixels probes to record electrical signals from hundreds of neurons in the hippocampus of anesthetized patients undergoing epilepsy surgery, the team found that the brain remains capable of identifying word categories, distinguishing unexpected sounds, and predicting the next word in a sentence while patients are completely unconscious.1
The findings, published in Nature on October 15, 2026, suggest that cognitive processes long thought to require consciousness may operate independently of it.1 According to Sameer Sheth, a professor leading the research, "the brain is far more active and capable in an unconscious state than previously thought."1 The work opens potential applications for speech prosthetic technology, which could eventually help patients with neurological injuries recover communication abilities.1 However, the researchers emphasized that their results were obtained using only one specific form of anesthesia and cannot automatically be extended to other anesthetic methods or different states of unconsciousness.1
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