斯坦陵布什大学的科学家利用二维液相色谱法结合高分辨率质量分析法，在南非商业种植的三个大麻品种的叶片中首次发现了16种类黄酮生物碱和79种酚类化合物。1其中25种酚类化合物此前从未在大麻中被报告过，这表明通常被视为废弃物的大麻叶片可能含有丰富的具有生物医学潜力的化合物。1
虽然大麻已知含有750多种代谢物，但这项研究通过先进的分析技术揭示了之前未被发现的化学多样性。1研究成果已发表在《色谱学杂志A》上。1
Scientists at Stellenbosch University have identified previously unknown chemical compounds in cannabis leaves using advanced analytical techniques.1 Researchers detected 79 phenolic compounds in three commercial cannabis varieties cultivated in South Africa, of which 25 had never been reported in cannabis before.1 Additionally, 16 compounds were preliminarily identified as flavonoid alkaloids, marking the first evidence of these substances in cannabis leaves.1
The findings suggest that cannabis leaves, typically discarded as waste material, may contain a rich reservoir of biomedically significant compounds.1 The research employed two-dimensional liquid chromatography combined with high-resolution mass spectrometry to conduct the analysis.1 Cannabis is already known to contain over 750 metabolites.1 The study has been published in the Journal of Chromatography A under DOI: 10.1016/j.chroma.2025.466023.1
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