英国曼彻斯特大学研究团队开发了一种非侵入性检测方法，通过采集尿液和阴道液体样本来筛查绝经后出血女性的子宫癌风险1。该检测方法在1,864名来自英国西北部7家医院、患有绝经后出血症状的女性中进行了临床验证1。研究结果显示，该测试在99例确诊癌症患者中识别了80例，对未患子宫癌的女性返回正确阴性结果的准确性达到93%1。
绝经后出血仅在5%至10%的患者中预示潜在癌症1。该测试可用于将高风险女性划分出来接受紧急检查，同时使低风险女性免除立即进行侵入性检测的需要1。研究人员表示，这种方法"有可能每年为数千名女性改变护理方式"1。该研究已发表于《柳叶刀妇产科、妇女与健康杂志》1。
Researchers at the University of Manchester have created a non-invasive screening method that identifies endometrial cancer in women experiencing postmenopausal bleeding by analyzing urine and vaginal fluid samples.1 In a study involving 1,864 women from seven hospitals in northwest England, the test detected 80 of 99 confirmed cancer cases, achieving approximately 81% sensitivity, while returning correct negative results for 93% of women without womb cancer.1 The findings, published in The Lancet Obstetrics, Gynaecology and Women's Health, demonstrate the potential for the approach to stratify high-risk patients for urgent investigation while sparing low-risk women from immediate invasive procedures.1
Postmenopausal bleeding occurs in only 5% to 10% of cases due to underlying cancer, yet hundreds of thousands of women worldwide receive an endometrial cancer diagnosis annually.1 Professor Emma Davidson stated that "this approach has the potential to change the way care is delivered for thousands of women every year."1
评论
还没有评论，欢迎留下第一条。