丹麦技术大学、哥本哈根大学和伦敦大学学院等机构的研究团队开发了一种名为微流体轴向电极(mAxialtrode)的脑植入装置,能够同时完成神经信号记录、药物递送和多脑区刺激三项功能1。这项研究已于2026年9月21日发表在《Advanced Science》期刊第13卷第18期上1。
该植入物设计精巧,直径小于0.5毫米,由软质类塑料材质的光纤和微通道组成1。其中包含8条微通道,药物递送点之间间隔近3毫米1。研究团队已在活体小鼠中成功验证了该装置的多项功能,包括利用蓝光和红光进行神经细胞刺激、记录浅层和深层脑区的电活动,以及在不同深度注射物质1。
研究人员Kunyang Sui指出,这项创新使得"几种能力可以结合在单个植入物中",而该植入物采用的软质光纤材料则能够最大程度地减少对脑组织的损伤1。这一多功能植入技术为癫痫等神经疾病的研究和治疗展现了潜在应用前景1。
Researchers from Denmark Technical University, University of Copenhagen, University College London, and other institutions have developed a flexible needle-thin brain implant capable of simultaneously recording neural signals, delivering drugs, and stimulating multiple brain regions 1. The device, called mAxialtrode, measures less than 0.5 millimeters in diameter and consists of optical fibers and microchannels 1. According to Kunyang Sui, a member of the research team, "several capabilities can be combined in a single implant," and the new device is "made of soft, plastic-like optical fiber" 1.
The implant features eight microchannels with drug delivery points spaced approximately 3 millimeters apart 1. In laboratory testing with live mice, the implant demonstrated blue and red light neural cell stimulation, electrical activity recording from both shallow and deep brain regions, and substance injection at multiple depths 1. The research was published in Advanced Science on September 21, 2026, in volume 13, issue 18 1. These capabilities suggest potential applications in researching and treating neurological conditions such as epilepsy 1.
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