多伦多大学工程师团队研发了一种新型染料敏化纳米粒子,能够在极低浓度下检测化学物质,并区分结构异构体等几乎相同的分子1。这些纳米粒子通过上转换过程将低能光子转化为高能光子,产生可测量的明亮光学信号1。相比未敏化的上转换纳米粒子,新型纳米粒子的亮度提高约150倍,相比现有最优化常规结构也提高约50倍1。
该创新采用了含锂、镥和氟的新型基质材料,替代了原有的钠、钇和氟组成1。这种设计使纳米粒子可以通过近红外光激发,仅需使用低成本激光即可操作1。该研究由Kai Huang教授团队主持,PhD学生Jiaze Wu为第一作者,已发表于《美国化学学会期刊》2026年第148卷第35期1。
Engineers at the University of Toronto have developed dye-sensitized nanoparticles capable of detecting chemical substances at extremely low concentrations and distinguishing between nearly identical molecules 1. The nanoparticles work through an upconversion process that converts low-energy photons into high-energy photons, generating a measurable bright optical signal 1.
The brightness of these new nanoparticles exceeds that of unsensitized upconversion nanoparticles by approximately 150 times and surpasses the best-performing conventional structures by roughly 50 times 1. The team achieved this advancement by employing a novel matrix composition containing lithium, lutetium, and fluorine, replacing the previous sodium, yttrium, and fluorine-based structure 1. A key capability of these nanoparticles is their ability to differentiate between structural isomers—molecules with identical atom types and quantities but different arrangements 1. The particles can be excited using near-infrared light and operated with low-cost lasers 1.
The research, led by Professor Kai Huang with PhD student Jiaze Wu as the first author, was published in the Journal of the American Chemical Society in 2026, volume 148, issue 35 1.
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