加州大学伯克利分校研究人员通过分析蝙蝠基因组,发现了隐藏在长寿蝙蝠DNA中的抗癌和抗病遗传秘密。1研究人员分析了8个鼠耳蝠属基因组,发现长寿蝙蝠具有更强的免疫防御能力和独特的受损细胞清除策略,这些特征可能为人类开发新的衰老和疾病防御方法提供启发。1这项研究已于2026年9月11日发表在《Nature》期刊上。1
研究团队收集了来自32种蝙蝠共259个个体的细胞培养物进行分析。1研究人员发现,黑色鼠耳蝠的寿命约为7年,而勃兰特氏鼠耳蝠可存活约50年,其中一只勃兰特氏鼠耳蝠在欧洲被标记后50年被重新捕获。1蝙蝠占所有哺乳动物物种的20%,已知有1511个蝙蝠物种,其中Myotis属约有139个物种。1该研究经费来自美国国立卫生研究院和国家科学基金会的支持。1
Researchers at UC Berkeley have uncovered genetic clues to longevity and disease resistance buried within bat DNA, potentially opening new avenues for understanding aging and developing defenses against illness in humans. 1 The team analyzed genomes from eight species within the Myotis genus and identified that long-lived bats possess enhanced immune defenses and distinctive mechanisms for clearing damaged cells—characteristics that could inform strategies to combat age-related decline. 1
The study, published in Nature on September 11, 2026, examined cell cultures from 259 individuals across 32 bat species. 1 The research revealed striking longevity differences among bats: while black myotis (Myotis nigricans) live approximately seven years, Brandt's myotis can survive roughly 50 years, as evidenced by a European individual recaptured 50 years after initial tagging. 1 Bats represent a significant portion of mammalian diversity, comprising 20 percent of all mammalian species, with approximately 1,511 known bat species and roughly 139 species within the Myotis genus alone. 1 The research was funded by the National Institutes of Health and the National Science Foundation. 1
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